Epimeric methylsulfinyladenosine derivatives from the marine ascidian Herdmania momus.

ABSTRACT: Investigation of the secondary metabolites of the ascidian Herdmania momus led to the isolation and characterization of four new nucleoside derivatives (1-4). Structural studies showed that these derivatives represent a series of rare methylsulfinyladenosine derivatives of interconvertible transesterification isomers and/or sulfinyl epimers. The antiviral activities of these rare nucleosides were evaluated against a series of human pathogenic viruses.

SUBMITTER: Li JL 

PROVIDER: S-EPMC7127152 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature