Ontology highlight
ABSTRACT:
SUBMITTER: Zhong Y
PROVIDER: S-EPMC7127588 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Reproductive toxicology (Elmsford, N.Y.) 20170816
Hepatitis B virus (HBV) can invade the male germline, and sperm-introduced HBV genes could be transcribed in embryo. This study was to explore whether viral gene transcription is regulated by host genes. Embryos were produced by in vitro fertilization of hamster oocytes with human sperm containing the HBV genome. Total RNA extracted from test and control embryos were subjected to SMART-PCR, SSH, microarray hybridization, sequencing and BLAST analysis. Twenty-nine sequences showing significant id ...[more]