Risk and protective factors for repeated overdose after opioid overdose survival.

ABSTRACT:

Background

Nonfatal opioid overdose (OD) is an opportunity to identify patients who may benefit from interventions to reduce repeated overdose (rOD). In this study, we sought to determine risk and protective factors associated with rOD.

Methods

In this retrospective cohort study of 4,155 patients aged 18-64 who presented to one of 16 emergency departments in a single Western Pennsylvania health system between July 2015 and January 2018 for index opioid overdose (iOD) and survived to discharge, we identified demographic and clinical factors association with rOD within one-year. Relative risk of repeated opioid overdose was estimated using adjusted Cox proportional hazard ratios (aHRs).

Results

14.9 % of patients (95 % CI 13.9-16.1) had a rOD, with 29 % occurring within

SUBMITTER: Suffoletto B 

PROVIDER: S-EPMC7127977 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature