Experimental duplication of bilaterian body axes in spider embryos: Holm's organizer and self-regulation of embryonic fields.

ABSTRACT: Bilaterally symmetric body plans of vertebrates and arthropods are defined by a single set of two orthogonal axes, the anterior-posterior (or head-tail) and dorsal-ventral axes. In vertebrates, and especially amphibians, complete or partial doubling of the bilaterian body axes can be induced by two different types of embryological manipulations: transplantation of an organizer region or bi-sectioning of an embryo. Such axis doubling relies on the ability of embryonic fields to flexibly respond to the situation and self-regulate toward forming a whole body. This phenomenon has facilitated experimental efforts to investigate the mechanisms of vertebrate body axes formation. However, few studies have addressed the self-regulatory capabilities of embryonic fields associated with body axes form

SUBMITTER: Oda H 

PROVIDER: S-EPMC7128006 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature