Honey bees harbor a diverse gut virome engaging in nested strain-level interactions with the microbiota.

ABSTRACT: The honey bee gut microbiota influences bee health and has become an important model to study the ecology and evolution of microbiota-host interactions. Yet, little is known about the phage community associated with the bee gut, despite its potential to modulate bacterial diversity or to govern important symbiotic functions. Here we analyzed two metagenomes derived from virus-like particles, analyzed the prevalence of the identified phages across 73 bacterial metagenomes from individual bees, and tested the host range of isolated phages. Our results show that the honey bee gut virome is composed of at least 118 distinct clusters corresponding to both temperate and lytic phages and representing novel genera with a large repertoire of unknown gene functions. We find that the phage community

SUBMITTER: Bonilla-Rosso G 

PROVIDER: S-EPMC7132132 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature