Task-Modulated Corticocortical Synchrony in the Cognitive-Motor Network Supporting Handwriting.

ABSTRACT: Both motor and cognitive aspects of behavior depend on dynamic, accurately timed neural processes in large-scale brain networks. Here, we studied synchronous interplay between cortical regions during production of cognitive-motor sequences in humans. Specifically, variants of handwriting that differed in motor variability, linguistic content, and memorization of movement cues were contrasted to unveil functional sensitivity of corticocortical connections. Data-driven magnetoencephalography mapping (n = 10) uncovered modulation of mostly left-hemispheric corticocortical interactions, as quantified by relative changes in phase synchronization. At low frequencies (~2-13 Hz), enhanced frontoparietal synchrony was related to regular handwriting, whereas premotor cortical regions synchronized fo

SUBMITTER: Saarinen T 

PROVIDER: S-EPMC7132916 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature