Unifying the Notions of Modularity and Core-Periphery Structure in Functional Brain Networks during Youth.

ABSTRACT: At rest, human brain functional networks display striking modular architecture in which coherent clusters of brain regions are activated. The modular account of brain function is pervasive, reliable, and reproducible. Yet, a complementary perspective posits a core-periphery or rich-club account of brain function, where hubs are densely interconnected with one another, allowing for integrative processing. Unifying these two perspectives has remained difficult due to the fact that the methodological tools to identify modules are entirely distinct from the methodological tools to identify core-periphery structure. Here, we leverage a recently-developed model-based approach-the weighted stochastic block model-that simultaneously uncovers modular and core-periphery structure, and we apply it to

SUBMITTER: Gu S 

PROVIDER: S-EPMC7132934 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature