Household presentation of acute gastroenteritis in a primary care sentinel network: retrospective database studies.

ABSTRACT:

Background

Acute gastroenteritis (AGE) is a highly transmissible condition spreading rapidly between individuals and within households. Rotavirus vaccination was introduced in the UK in 2013. The study objectives were to investigate how acute gastroenteritis incidence changed over 25 years and household incidence of AGE since 2013.

Methods

Repeated cross-sectional study of Royal College of General Practitioners Research and Surveillance Centre network. We used a negative binomial model to report incidence rate ratio (IRR) using the last 5 years data. We also conducted a retrospective cohort analysis, using a shared gamma frailty model (2013-2017). We explored the impact of child under 5- years, household size, socioeconomic status quintile, and rurality.

Results

In th

SUBMITTER: de Lusignan S 

PROVIDER: S-EPMC7132989 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature