Prognostic Value of Ambulatory Blood Pressure Load in Pediatric CKD.

ABSTRACT:

Background and objectives

Elevated BP load is part of the criteria for ambulatory hypertension in pediatric but not adult guidelines. Our objectives were to determine the prevalence of isolated BP load elevation and associated risk with adverse outcomes in children with CKD, and to ascertain whether BP load offers risk discrimination independently or in conjunction with mean ambulatory BPs.

Design, setting, participants, & measurements

We studied 533 children in the CKD in Children (CKiD) Study to determine the prevalence of normotension, isolated BP load elevation (≥25% of all readings elevated but mean BP normal), and ambulatory hypertension. We examined the association between these categories of BP control and adverse outcomes (left ventricular hypertrophy [LVH] or ESKD)

SUBMITTER: Lee J 

PROVIDER: S-EPMC7133128 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature