Prevalence of Ototoxicity Following Hematopoietic Stem Cell Transplantation in Pediatric Patients.

ABSTRACT: The use of hematopoietic stem cell transplantation (HSCT) is increasing for a variety of diseases. Ototoxicity from this procedure has not been extensively studied. A retrospective chart review examined 275 patients from this institution who underwent HSCT between January 1, 2007, and April 30, 2017. Data extracted included therapy before HSCT and the subsequent course of transplantation. Evaluable patients had complete medical records and interpretable audiograms available. Ototoxicity constituted significant threshold changes from baseline or changes in International Society of Pediatric Oncology/Boston Ototoxicity Grading Scale (SIOP) grade comparing audiogram results just before HSCT with those following the transplantation procedure. A total of 147 patients were evaluable. Ototoxicity

SUBMITTER: Gertson K 

PROVIDER: S-EPMC7135908 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature