Clinical presentation of young people (10-24 years old) with brain tumors: results from the international MOBI-Kids study.

ABSTRACT:

Introduction

We used data from MOBI-Kids, a 14-country international collaborative case-control study of brain tumors (BTs), to study clinical characteristics of the tumors in older children (10 years or older), adolescents and young adults (up to the age of 24).

Methods

Information from clinical records was obtained for 899 BT cases, including signs and symptoms, symptom onset, diagnosis date, tumor type and location.

Results

Overall, 64% of all tumors were low-grade, 76% were neuroepithelial tumors and 62% gliomas. There were more males than females among neuroepithelial and embryonal tumor cases, but more females with meningeal tumors. The most frequent locations were cerebellum (22%) and frontal (16%) lobe. The most frequent symptom was headaches (60%), overall, a

SUBMITTER: Zumel-Marne A 

PROVIDER: S-EPMC7136306 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature