Project description:Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus (DM). It is not diagnosed or managed properly in the majority of patients, because its pathogenesis remains controversial. In this study, using microarray-based genome-wide expression analyses, we sought to identify both common and distinct mechanisms underlying the pathogenesis of DM and DPN. The results demonstrated that down-regulation of the neurotrophin-MAPK signaling pathway may be the major mechanism of DPN pathogenesis, thus providing a potential approach for DPN treatment.

2017-03-09 | GSE95849 | GEO

Diabetic neuropathy: mechanisms, emerging treatments, and subtypes.

Project description: Not available

| S-EPMC5084622 | biostudies-literature

Diabetic neuropathy: what does the future hold?

Project description: Not available

| S-EPMC7150623 | biostudies-literature

Genetic and Epigenomic Modifiers of Diabetic Neuropathy.

Project description: Not available

| S-EPMC8124699 | biostudies-literature

Greater corneal nerve loss at the inferior whorl is related to the presence of diabetic neuropathy and painful diabetic neuropathy.

Project description: Not available