Prediction of Short- and Long-Term Outcomes in Childhood Nephrotic Syndrome.

ABSTRACT:

Introduction

It is unknown whether steroid sensitivity and other putative risk factors collected at baseline can predict the disease course of idiopathic nephrotic syndrome in childhood. We determined whether demographic, clinical, and family reported factors at presentation can predict outcomes in idiopathic nephrotic syndrome.

Methods

An observational cohort of 631 children aged 1 to 18 years diagnosed with idiopathic nephrotic syndrome between 1993 and 2016 were followed up until clinic discharge, 18 years of age, end-stage kidney disease (ESKD), or the last clinic visit. Baseline characteristics were age, sex, ethnicity, and initial steroid sensitivity. Of these, 287 (38%) children also reported any family history of kidney disease, preceding infection, microscopic hemat

SUBMITTER: Carter SA 

PROVIDER: S-EPMC7136435 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature