Association Between Bedroom Particulate Matter Filtration and Changes in Airway Pathophysiology in Children With Asthma.

ABSTRACT:

Importance

Fine particles (particulate matter 2.5 μm [PM2.5]), a ubiquitous air pollutant, can deposit in the small airways that play a vital role in asthma. It appears to be unknown whether the use of a PM2.5 filtration device can improve small airway physiology and respiratory inflammation in children with asthma.

Objective

To discover what pathophysiological changes in the small airways are associated with using a PM2.5-removing device in the bedrooms of children with asthma.

Design, setting, and participants

Children with mild or moderate asthma were enrolled in this double-blind, crossover study. The participants used a true filtration device and a sham filtration device in their bedrooms in a random order for 2 weeks each with a 2-week washout interval. The stud

SUBMITTER: Cui X 

PROVIDER: S-EPMC7136863 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature