Stable intronic sequence RNAs (sisRNAs) are selected regions in introns with distinct properties.

ABSTRACT:

Background

Stable introns and intronic fragments make up the largest population of RNA in the oocyte nucleus of the frog Xenopus tropicalis. These stable intronic sequence RNAs (sisRNAs) persist through the onset of zygotic transcription when synchronous cell division has ended, and the developing embryo consists of approximately 8000 cells. Despite their abundance, the sequence properties and biological function of sisRNAs are just beginning to be understood.

Results

To characterize this population of non-coding RNA, we identified all of the sisRNAs in the X. tropicalis oocyte nucleus using published high-throughput RNA sequencing data. Our analysis revealed that sisRNAs, have an average length of ~ 360 nt, are widely expressed from genes with multiple introns, and are deri

SUBMITTER: Jin J 

PROVIDER: S-EPMC7137253 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature