The predictive value of lncRNA MIR31HG expression on clinical outcomes in patients with solid malignant tumors.

ABSTRACT:

Background

Emerging studies have explored the prognostic value of MIR31HG in cancers, but its role remains elusive. Herein, we aimed to summarize the prognostic potential of MIR31HG in this study.

Methods

Several databases were searched for literature retrieval on Dec 5, 2019. Overall and subgroup analyses were conducted to measure the relationship between MIR31HG expression and clinical outcomes. Moreover, GEPIA was applied for validation of prognostic value of MIR31HG in tumor patients in TCGA dataset.

Results

Overall, seventeen studies with 2573 patients were enrolled. Compared to counterparts, those patients with high MIR31HG expression tended to have shorter RFS. Notably, MIR31HG overexpression predicted unfavorable OS in lung cancer. By contrast, gastrointestina

SUBMITTER: Tu C 

PROVIDER: S-EPMC7137300 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature