The influence of adipose-derived stromal vascular fraction cells on the treatment of knee osteoarthritis.

ABSTRACT:

Background

Adipose-derived stromal vascular fraction (SVF) cells are a mixed cell population that includes cells with multilineage potential, similar to bone marrow-derived mesenchymal stem cells. Our purpose is to investigate the influence of SVF cells in patients with knee osteoarthritis (OA) and the short-term treatment effects.

Methods

Fifty-seven patients were enrolled and treated with intra-articular injection of 2.5 × 10⁷ SVF cells into the knee joint between September 2017 and March 2018. All patients were followed up for 12 months or longer. Mean age at treatment and follow-up period were 69.4 ± 6.9 years and 13.7 ± 2.0 months, respectively. The mean preoperative hip-knee-ankle angle was 6.7 ± 3.6°. SVF cells were prepared using the Celution®800/CRS syste

SUBMITTER: Tsubosaka M 

PROVIDER: S-EPMC7137313 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature