Origin and evolution of the Rax homeobox gene by comprehensive evolutionary analysis.
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ABSTRACT:
SUBMITTER: Kon T
PROVIDER: S-EPMC7137802 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
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Origin and evolution of the Rax homeobox gene by comprehensive evolutionary analysis.
Kon Tetsuo T Furukawa Takahisa T
FEBS open bio 20200319 4
Rax is one of the key transcription factors crucial for vertebrate eye development. In this study, we conducted comprehensive evolutionary analysis of Rax. We found that Bilateria and Cnidaria possess Rax, but Placozoa, Porifera, and Ctenophora do not, implying that the origin of the Rax gene dates back to the common ancestor of Cnidaria and Bilateria. The results of molecular phylogenetic and synteny analyses on Rax loci between jawed and jawless vertebrates indicate that segmental duplication ...[more]
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