Isoflavone Intake and the Risk of Coronary Heart Disease in US Men and Women: Results From 3 Prospective Cohort Studies.

ABSTRACT:

Background

Whether soy products confer health benefits related to coronary heart disease (CHD) remains controversial because of inconsistent evidence.

Methods

A total of 74 241 women from the NHS (Nurses' Health Study; 1984-2012), 94 233 women from the NHSII (Nurses' Health Study II; 1991-2013), and 42 226 men from the Health Professionals Follow-Up Study (1986-2012), who were free of cardiovascular disease and cancer at baseline, were included in the present analysis. Dietary data were updated every 2 to 4 years using a validated food frequency questionnaire. Nonfatal myocardial infarction and CHD deaths were adjudicated through reviewing medical records, death certificates, and other medical documents.

Results

In these cohorts, 8359 incident CHD cases were documente

SUBMITTER: Ma L 

PROVIDER: S-EPMC7138725 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature