Dataset Information
Differential Effects of Alternate-Day Fasting Versus Daily Calorie Restriction on Insulin Resistance.
Ontology highlight
ABSTRACT: Objective
This study compared the effects of alternate-day fasting (ADF) with those of daily calorie restriction (CR) on body weight and glucoregulatory factors in adults with overweight or obesity and insulin resistance.Methods
This secondary analysis examined the data of insulin-resistant individuals (n?=?43) who participated in a 12-month study that compared ADF (25% energy needs on "fast days"; 125% energy needs on alternating "feast days") with CR (75% energy needs every day) and a control group regimen.Results
In insulin-resistant participants, weight loss was not different between ADF (-8%?±?2%) and CR (-6%?±?1%) by month 12, relative to controls (P?ConclusionsThese findings suggest that ADF may produce greater reductions in fasting insulin and insulin resistance compared with CR in insulin-resistant participants despite similar decreases in body weight.
SUBMITTER: Gabel K
PROVIDER: S-EPMC7138754 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
Differential Effects of Alternate-Day Fasting Versus Daily Calorie Restriction on Insulin Resistance.
Obesity (Silver Spring, Md.) 20190722 9
<h4>Objective</h4>This study compared the effects of alternate-day fasting (ADF) with those of daily calorie restriction (CR) on body weight and glucoregulatory factors in adults with overweight or obesity and insulin resistance.<h4>Methods</h4>This secondary analysis examined the data of insulin-resistant individuals (n = 43) who participated in a 12-month study that compared ADF (25% energy needs on "fast days"; 125% energy needs on alternating "feast days") with CR (75% energy needs every day ...[more]
