Continuous positive airway pressure improves respiratory mechanics and efficiency of neural drive in stable COPD: an exploratory study.

ABSTRACT:

Background

Continuous positive airway pressure (CPAP) is a major treatment strategy for severe chronic obstructive pulmonary disease (COPD), especially with respiratory failure. However, it remains inconclusive whether CPAP affects respiratory mechanics and neural drive in stable COPD patients without respiratory failure.

Methods

Twenty-two COPD patients without respiratory failure received CPAP starting from 4 to 10 cmH₂O in 1 cmH₂O increments. Respiratory pattern, end expiatory lung volume (EELV), dynamic PEEPi (PEEPi_dyn), airway resistance (Raw), pressure-time product of diaphragmatic pressure (PTPdi) and esophageal pressure (PTPeso), root mean square (RMS) of diaphragm electromyogram (EMGdi) and ratio of ventilation (Ve) to EMGdi (i.e., V

SUBMITTER: Wang K 

PROVIDER: S-EPMC7139021 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature