Clinical outcomes and toxicity predictors of thoracic re-irradiation for locoregionally recurrent lung cancer.

ABSTRACT:

Background and purpose

Thoracic re-irradiation may be an alternative treatment for lung cancer patients who develop intrathoracic locoregional recurrence without systemic progression. This study aimed to retrospectively assess locoregional control, clinical outcomes, and toxicities in lung cancer patients who received thoracic re-irradiation.

Materials and methods

We retrospectively reviewed 50 lung cancer patients who received thoracic re-irradiation using conventional photon radiotherapy (RT) and stereotactic body radiotherapy (SBRT) between 2009 and 2017. The correlations of clinicopathologic factors, treatment factors, and dosimetric factors of RT with time to local progression (TTLP), progression-free survival (PFS), and overall survival (OS) after starting thoracic re-

SUBMITTER: Yang WC 

PROVIDER: S-EPMC7139144 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature