Animal Models in Microbeam Radiation Therapy: A Scoping Review.

ABSTRACT:

Background

Microbeam Radiation Therapy (MRT) is an innovative approach in radiation oncology where a collimator subdivides the homogeneous radiation field into an array of co-planar, high-dose beams which are tens of micrometres wide and separated by a few hundred micrometres.

Objective

This scoping review was conducted to map the available evidence and provide a comprehensive overview of the similarities, differences, and outcomes of all experiments that have employed animal models in MRT.

Methods

We considered articles that employed animal models for the purpose of studying the effects of MRT. We searched in seven databases for published and unpublished literature. Two independent reviewers screened citations for inclusion. Data extraction was done by three reviewer

SUBMITTER: Fernandez-Palomo C 

PROVIDER: S-EPMC7139755 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature