Inferring Effective Population Size and Divergence Time in the Lithuanian Population According to High-Density Genotyping Data.

ABSTRACT: The prehistory of the Lithuanian population and genetic relationship to other populations are poorly studied. Thus, the Lithuanian population, as an object of study, is interesting due to its partial isolation with genetic distinctiveness within the European context and with preserved ancient genetic composition. The main objects of this study was to infer demographic parameters, effective population size (Ne), and divergence time using high-density single nucleotide polymorphism (SNP) genotyping data generated with the Illumina HumanOmmiExpress-12v1.1 array in 295 individuals from the Lithuanian population and to compare our data with other populations from the Human Genome Cell Line Diversity Panel (HGDP-CEPH). We also aimed to reconstruct past events between the main ethnolinguistic reg

SUBMITTER: Urnikyte A 

PROVIDER: S-EPMC7140885 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature