Extracellular electrical conductivity property imaging by decomposition of high-frequency conductivity at Larmor-frequency using multi-b-value diffusion-weighted imaging.

ABSTRACT: Magnetic resonance electrical properties tomography (MREPT) uses the B1 mapping technique to provide the high-frequency conductivity distribution at Larmor frequency that simultaneously reflects the intracellular and extracellular effects. In biological tissues, the electrical conductivity can be described as the concentration and mobility of charge carriers. For the water molecule diffusivity, diffusion weighted imaging (DWI) measures the random Brownian motion of water molecules within biological tissues. The DWI data can quantitatively access the mobility of microscopic water molecules within biological tissues. By measuring multi-b-value DWI data and the recovered high-frequency conductivity at Larmor frequency, we propose a new method to decompose the conductivity into the total ion c

SUBMITTER: Lee MB 

PROVIDER: S-EPMC7141654 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature