Comparing 6-minute walk versus treadmill walking distance as outcomes in randomized trials of peripheral artery disease.

ABSTRACT:

Background

Randomized trials of people with peripheral artery disease (PAD) and intermittent claudication have traditionally used maximal treadmill walking distance as the primary outcome, but the 6-minute walk test is increasingly used as a primary outcome in randomized trials of PAD. This study compared relative changes in maximal treadmill walking distance versus 6-minute walk distance in response to a therapeutic intervention or control in randomized trials of participants with PAD.

Methods

Data from four randomized trials of therapeutic interventions in participants with PAD that measured both 6-minute walk and treadmill walking performance at baseline and the 6-month follow-up were combined. Two trials studied supervised treadmill exercise, one studied home-based walki

SUBMITTER: McDermott MM 

PROVIDER: S-EPMC7141750 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature