Incidence and time trends of anal cancer among people living with HIV in Australia.

ABSTRACT:

Background

Anal cancer incidence increased markedly in people living with HIV (PLWHIV) after the introduction of HAART, but in a few setting settings, recent declines have been reported. We report the incidence and time trends of anal cancer in PLWHIV in Australia.

Study design

A data linkage study between the National HIV Registries and the Australian Cancer Database.

Methods

Cases of anal squamous cell carcinoma (ASCC) in Australians aged 16 years and above diagnosed with HIV between 1982 and 2012 were identified. Standardized incidence ratios (SIRs) were calculated to compare incidence with that of the general population. Poisson regression models were developed to describe the time trends of ASCC over time and to compare ASCC risk within subgroups of PLWHIV.

Re

SUBMITTER: Jin F 

PROVIDER: S-EPMC7141812 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature