SimRVSequences: an R package to simulate genetic sequence data for pedigrees.

ABSTRACT:

Summary

We present the R package SimRVSequences to simulate sequence data for pedigrees. SimRVSequences allows for simulations of large numbers of single-nucleotide variants (SNVs) and scales well with increasing numbers of pedigrees. Users provide a sample of pedigrees and SNV data from a sample of unrelated individuals.

Availability and implementation

SimRVSequences is publicly-available on CRAN https://cran.r-project.org/web/packages/SimRVSequences/.

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Nieuwoudt C 

PROVIDER: S-EPMC7141864 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature