Insights into Thermophilic Plant Biomass Hydrolysis from Caldicellulosiruptor Systems Biology.

ABSTRACT: Plant polysaccharides continue to serve as a promising feedstock for bioproduct fermentation. However, the recalcitrant nature of plant biomass requires certain key enzymes, including cellobiohydrolases, for efficient solubilization of polysaccharides. Thermostable carbohydrate-active enzymes are sought for their stability and tolerance to other process parameters. Plant biomass degrading microbes found in biotopes like geothermally heated water sources, compost piles, and thermophilic digesters are a common source of thermostable enzymes. While traditional thermophilic enzyme discovery first focused on microbe isolation followed by functional characterization, metagenomic sequences are negating the initial need for species isolation. Here, we summarize the current state of knowledge about

SUBMITTER: Blumer-Schuette SE 

PROVIDER: S-EPMC7142884 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature