Differential Distribution of the wlaN and cgtB Genes, Associated with Guillain-Barre Syndrome, in Campylobacter jejuni Isolates from Humans, Broiler Chickens, and Wild Birds.

ABSTRACT: Campylobacter jejuni causes campylobacteriosis, a bacterial gastroenteritis with high incidence worldwide. Moreover, C. jejuni infection can trigger the polyneuropathic disorder denominated Guillain-Barré syndrome (GBS). The C. jejuni strains that can elicit GBS carry either wlaN or cgtB, coding both genes for a β-1,3-galactosyltransferase enzyme that is required for the production of sialylated lipooligosaccharide (LOS^SIAL). We described a differential prevalence of the genes wlaN and cgtB in C. jejuni isolates from three different ecological niches: humans, broiler chickens, and wild birds. The distribution of both genes, which is similar between broiler chicken and human isolates and distinct when compared to the wild bi

SUBMITTER: Guirado P 

PROVIDER: S-EPMC7142995 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature