BIPEP: Sequence-based Prediction of Biofilm Inhibitory Peptides Using a Combination of NMR and Physicochemical Descriptors.

ABSTRACT: Biofilms are biological systems that are formed by a community of microorganisms in which microbial cells are connected on a surface within a self-produced matrix of an extracellular polymeric substance. On some occasions, microorganisms use biofilms to protect themselves against the harmful effects of the host body immune system and the surrounding environment, hence increasing their chances of survival against the various anti-microbial agents. Biofilms play a crucial role in medicine and industry because of the problems they cause. Designing agents that inhibit bacterial biofilm formation is very costly and takes too much time in the laboratory to be discovered and validated. Therefore, developing computational tools for the prediction of biofilm inhibitor peptides is inevitable and imp

SUBMITTER: Fallah Atanaki F 

PROVIDER: S-EPMC7144140 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature