Effect of aspirin use on gastric cancer incidence and survival: A systematic review and meta-analysis.

ABSTRACT:

Background and aim

A number of recent studies have been published evaluating the chemopreventive effect of aspirin against gastric cancer, and an updated meta-analysis is required to evaluate this relationship further. This study presents a meta-analysis of studies examining the effect of aspirin on gastric cancer incidence and death.

Methods

The PUBMED and Cochrane Central Registration of Controlled Trials databases were searched for eligible studies published up to December 2018. Pooled risk ratios for gastric cancer incidence and death in aspirin users versus nonusers were determined using fixed- and random-effects models. The influence of the frequency of aspirin use, duration of aspirin use, and geographic location on gastric cancer incidence was evaluated.

Re

SUBMITTER: Niikura R 

PROVIDER: S-EPMC7144786 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature