Dynamic Functional Connectivity Patterns in Schizophrenia and the Relationship With Hallucinations.

ABSTRACT: There is a wealth of evidence showing aberrant functional connectivity (FC) in schizophrenia but with considerable variability in findings across studies. Dynamic FC is an extension of traditional static FC, in that such analyses allow for explorations of temporal changes in connectivity. Thereby they also provide more detailed information on connectivity abnormalities in psychiatric disorders such as schizophrenia. The current study investigated dynamic FC in a sample of 80 schizophrenia patients and 80 matched healthy control subjects, replicating previous findings of aberrant dwell times in specific FC states, and further supporting a role for default mode network (DMN) dysfunction. Furthermore, relationships with hallucinations, a core symptom of schizophrenia, were explored. Two measu

SUBMITTER: Weber S 

PROVIDER: S-EPMC7145395 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature