TDR Targets 6: driving drug discovery for human pathogens through intensive chemogenomic data integration.

ABSTRACT: The volume of biological, chemical and functional data deposited in the public domain is growing rapidly, thanks to next generation sequencing and highly-automated screening technologies. These datasets represent invaluable resources for drug discovery, particularly for less studied neglected disease pathogens. To leverage these datasets, smart and intensive data integration is required to guide computational inferences across diverse organisms. The TDR Targets chemogenomics resource integrates genomic data from human pathogens and model organisms along with information on bioactive compounds and their annotated activities. This report highlights the latest updates on the available data and functionality in TDR Targets 6. Based on chemogenomic network models providing links between inhibit

SUBMITTER: Uran Landaburu L 

PROVIDER: S-EPMC7145610 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature