DNAproDB: an expanded database and web-based tool for structural analysis of DNA-protein complexes.

ABSTRACT: DNAproDB (https://dnaprodb.usc.edu) is a web-based database and structural analysis tool that offers a combination of data visualization, data processing and search functionality that improves the speed and ease with which researchers can analyze, access and visualize structural data of DNA-protein complexes. In this paper, we report significant improvements made to DNAproDB since its initial release. DNAproDB now supports any DNA secondary structure from typical B-form DNA to single-stranded DNA to G-quadruplexes. We have updated the structure of our data files to support complex DNA conformations, multiple DNA-protein complexes within a DNAproDB entry and model indexing for analysis of ensemble data. Support for chemically modified residues and nucleotides has been significantly improved

SUBMITTER: Sagendorf JM 

PROVIDER: S-EPMC7145614 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature