The neXtProt knowledgebase in 2020: data, tools and usability improvements.

ABSTRACT: The neXtProt knowledgebase (https://www.nextprot.org) is an integrative resource providing both data on human protein and the tools to explore these. In order to provide comprehensive and up-to-date data, we evaluate and add new data sets. We describe the incorporation of three new data sets that provide expression, function, protein-protein binary interaction, post-translational modifications (PTM) and variant information. New SPARQL query examples illustrating uses of the new data were added. neXtProt has continued to develop tools for proteomics. We have improved the peptide uniqueness checker and have implemented a new protein digestion tool. Together, these tools make it possible to determine which proteases can be used to identify trypsin-resistant proteins by mass spectrometry. In t

SUBMITTER: Zahn-Zabal M 

PROVIDER: S-EPMC7145669 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature