Surgical versus Medical Castration for Metastatic Prostate Cancer: Use and Overall Survival in a National Cohort.

ABSTRACT:

Purpose

Surgical castration for metastatic prostate cancer is used less frequently than medical castration yet costs less, requires less followup and may be associated with fewer adverse effects. We evaluated temporal trends and factors associated with the use of surgical castration.

Materials and methods

This retrospective cohort study sampled 24,805 men with newly diagnosed (de novo) metastatic prostate cancer from a national cancer registry in the United States (2004 to 2016). Multivariable logistic regression assessed the association between sociodemographic factors and surgery. Multivariable Cox regression evaluated the association between castration type and overall survival.

Results

Overall 5.4% of men underwent surgical castration. This figure decreased from 8

SUBMITTER: Weiner AB 

PROVIDER: S-EPMC7145732 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature