Vitamin D and Abdominal Aortic Calcification in Older African American Women, the PODA Clinical Trial.

ABSTRACT: Abdominal aortic calcification (AAC) detected on lateral vertebral fracture assessment is associated with increased cardiovascular risk. Vitamin D deficiency and toxicity have been linked with vascular calcification. The objective of this study was to determine the effect of high-dose vitamin D on the progression of AAC. The Physical Performance, Osteoporosis and vitamin D in African American Women (PODA) is a randomized, clinical trial examining the effect of vitamin D. There were 14.7% subjects with AAC in the vitamin D group, compared to 12.1% in the placebo group at baseline. The prevalence of extended AAC at baseline was 6.4% in the vitamin D group and 3.5% in the placebo group. The extended calcification scores over time were not different between groups. There was no association bet

SUBMITTER: Brahmbhatt S 

PROVIDER: S-EPMC7146156 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature