Oral Microbiota Profile Associates with Sugar Intake and Taste Preference Genes.

ABSTRACT: Oral microbiota ecology is influenced by environmental and host conditions, but few studies have evaluated associations between untargeted measures of the entire oral microbiome and potentially relevant environmental and host factors. This study aimed to identify salivary microbiota cluster groups using hierarchical cluster analyses (Wards method) based on 16S rRNA gene amplicon sequencing, and identify lifestyle and host factors which were associated with these groups. Group members (n = 175) were distinctly separated by microbiota profiles and differed in reported sucrose intake and allelic variation in the taste-preference-associated genes TAS1R1 (rs731024) and GNAT3 (rs2074673). Groups with higher sucrose intake were either characterized by a wide panel of species

SUBMITTER: Esberg A 

PROVIDER: S-EPMC7146170 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature