First pass effect with contact aspiration and stent retrievers in the Aspiration versus Stent Retriever (ASTER) trial.

ABSTRACT:

Background

The 'first pass effect' (FPE), which was originally described with stent retrievers, designates a (near-)complete revascularization obtained after a single device pass with no rescue therapy, and is associated with improved clinical outcome and decreased mortality.

Objective

We report the rate and benefits of FPE in the Aspiration versus Stent Retriever (ASTER) trial.

Materials and methods

ASTER is a randomized trial comparing angiographic revascularization with the stent retriever (SR) and contact aspiration (CA) thrombectomy techniques, assessed by an external core laboratory using the modified Thrombolysis in Cerebral Infarction (mTICI) scale. Rates of FPE (defined by mTICI 2c/3 after a single pass with no rescue therapy) were compared between patients t

SUBMITTER: Ducroux C 

PROVIDER: S-EPMC7146919 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature