The role of intraoperative radiation therapy in resectable pancreatic cancer: a systematic review and meta-analysis.

ABSTRACT:

Purpose

Several studies investigating the role of intraoperative radiotherapy (IORT) in the treatment of resectable pancreatic cancer (PC) have been published; however, their results remain inconsistent. By conducting a systematic review and meta-analysis, this study aimed to compare clinical outcomes in patients with resectable PC who underwent surgery with or without IORT.

Methods and materials

The MEDLINE/PubMed, EMBASE, and Cochrane Library databases were searched to identify relevant studies published up to February 28, 2019. The main outcome measures included median survival time (MST), local recurrence (LR), postoperative complications, and operation-related mortality. Pooled effect estimates were obtained by performing a random-effects meta-analysis.

Results

A

SUBMITTER: Jin L 

PROVIDER: S-EPMC7147036 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature