Patterns and characteristics of cognitive functioning in older patients approaching end stage kidney disease, the COPE-study.

ABSTRACT:

Background

The prevalence of impaired cognitive functioning in older patients with end stage kidney disease (ESKD) is high. We aim to describe patterns of memory, executive function or psychomotor speed and to identify nephrologic, geriatric and neuroradiologic characteristics associated with cognitive impairment in older patients approaching ESKD who have not yet started with renal replacement therapy (RRT).

Methods

The COPE-study (Cognitive Decline in Older Patients with ESRD) is a prospective cohort study including 157 participants aged 65 years and older approaching ESKD (eGFR ≤20 ml/min/1.73 m²) prior to starting with RRT. In addition to routinely collected clinical parameters related to ESKD, such as vascular disease burden and parameters of metabolic distur

SUBMITTER: van Deudekom FJ 

PROVIDER: S-EPMC7147053 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature