Evaluation of radiation treatment volumes for unknown primaries of the head and neck in the era of FDG PET.

ABSTRACT: OBJECTIVES:Positron-emission tomography (PET) has improved identification of the primary tumor as well as occult nodal burden in cancer of the head and neck. Nevertheless, there are still patients where the primary tumor cannot be located. In these situations, the standard of care is comprehensive head and neck radiation therapy however it is unclear whether this is necessary. This study examines the effects of radiation treatment volume on outcomes among using data from two cancer centers in unknown primary carcinoma of the head and neck. METHODS:Patients received unilateral (n = 34), or bilateral radiation (n = 28). Patient factors such as age, gender, smoking history, and patterns of failure were compared using Mann Whitney U and Chi Square. Overall survival (OS) and disease free surviv

SUBMITTER: Platek A 

PROVIDER: S-EPMC7147765 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature