Faster 3D saturation-recovery based myocardial T1 mapping using a reduced number of saturation points and denoising.

ABSTRACT:

Purpose

To accelerate the acquisition of free-breathing 3D saturation-recovery-based (SASHA) myocardial T1 mapping by acquiring fewer saturation points in combination with a post-processing 3D denoising technique to maintain high accuracy and precision.

Methods

3D SASHA T1 mapping acquires nine T1-weighted images along the saturation recovery curve, resulting in long acquisition times. In this work, we propose to accelerate conventional cardiac T1 mapping by reducing the number of saturation points. High T1 accuracy and low standard deviation (as a surrogate for precision) is maintained by applying a 3D denoising technique to the T1-weighted images prior to pixel-wise T1 fitting. The proposed approach was evaluated on a T1 phantom and 20 healthy subjects, by varying the numb

SUBMITTER: Nordio G 

PROVIDER: S-EPMC7147792 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature