Analytical considerations associated with implementing M²⁺ correction factors to address false positives on As and Se within U.S. EPA method 200.8.

ABSTRACT: Rare earth elements (REE) can produce M²⁺ ions in ICP-MS and ¹⁵⁰Nd²⁺, ¹⁵⁰Sm²⁺, and ¹⁵⁶Gd²⁺ can produce false positives on ⁷⁵As and ⁷⁸Se. Alternative instrumental tuning conditions, that utilize lower He flows within the collision cell, reduce these false positives by a factor of 2 (to 0.8 ppb As and 19 ppb Se in solutions containing 50 ppb Nd and Gd) with comparable ¹⁶O³⁵Cl⁺ reduction (<100 ppt false ⁵¹V in 0.4% HCl) and Se sensitivity (DL < 1 ppb). Further reduction of these false positives is achieved by estimating the M²⁺ correction factors and utilizing them in the interference-correction software. Approaches to estimating the M²

SUBMITTER: Smith SW 

PROVIDER: S-EPMC7147816 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature