Expanding construct validity of established and new PROMIS Pediatric measures for children and adolescents receiving cancer treatment.

ABSTRACT: BACKGROUND:The Patient-Reported Outcomes Measurement Information System (PROMIS) Pediatric measures were designed to assess symptoms and functioning in children and adolescents. The study goal was to evaluate the validity and responsiveness of the PROMIS Pediatric measures in a diverse cohort of children with cancer. METHODS:Children (7-18 years) from nine pediatric oncology hospitals completed surveys at 72 hours preceding treatment initiation (T1) and at follow-up (T2) approximately 7 to 17 days later for chemotherapy, and 4+ weeks later for radiation. Children completed PROMIS Pediatric measures (Mobility, Pain Interference, Fatigue, Depressive Symptoms, Anxiety, Psychological Stress), Memorial Symptom Assessment Scale (MSAS), and global impressions of change (GIC) questions on their sy

SUBMITTER: Reeve BB 

PROVIDER: S-EPMC7147933 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature