Cellular immune responses in amniotic fluid of women with preterm clinical chorioamnionitis.

ABSTRACT:

Objective

Preterm birth is the leading cause of neonatal morbidity and mortality worldwide. Some preterm births are associated with clinical chorioamnionitis; yet, this condition has been poorly investigated. Herein, we characterized the amniotic fluid cellular immune responses in women with preterm clinical chorioamnionitis.

Methods and subjects

Amniotic fluid samples were obtained from women with preterm clinical chorioamnionitis and a positive or negative microbiological culture (n = 17). The cellular composition of amniotic fluid was evaluated using fluorescence microscopy, scanning and transmission electron microscopy, and flow cytometry. Women without preterm clinical chorioamnionitis were also examined (n = 10).

Results

Amniotic fluid from women with preterm cl

SUBMITTER: Galaz J 

PROVIDER: S-EPMC7147946 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature