Toxigenic Vibrio cholerae evolution and establishment of reservoirs in aquatic ecosystems.

ABSTRACT: The spread of cholera in the midst of an epidemic is largely driven by direct transmission from person to person, although it is well-recognized that Vibrio cholerae is also capable of growth and long-term survival in aquatic ecosystems. While prior studies have shown that aquatic reservoirs are important in the persistence of the disease on the Indian subcontinent, an epidemiological view postulating that locally evolving environmental V. cholerae contributes to outbreaks outside Asia remains debated. The single-source introduction of toxigenic V. cholerae O1 in Haiti, one of the largest outbreaks occurring this century, with 812,586 suspected cases and 9,606 deaths reported through July 2018, provided a unique opportunity to evaluate the role of aquatic reservoirs an

SUBMITTER: Mavian C 

PROVIDER: S-EPMC7149412 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature