Prevalence and Risk Factors for Opioid-Induced Constipation in an Older National Veteran Cohort.

ABSTRACT:

Objectives

This research describes the prevalence and covariates associated with opioid-induced constipation (OIC) in an observational cohort study utilizing a national veteran cohort and integrated data from the Center for Medicare and Medicaid Services (CMS).

Methods

A cohort of 152,904 veterans with encounters between 1 January 2008 and 30 November 2010, an exposure to opioids of 30 days or more, and no exposure in the prior year was developed to establish existing conditions and medications at the start of the opioid exposure and determining outcomes through the end of exposure. OIC was identified through additions/changes in laxative prescriptions, all-cause constipation identification through diagnosis, or constipation related procedures in the presence of opioid expos

SUBMITTER: FitzHenry F 

PROVIDER: S-EPMC7149448 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature