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Treatment of pre- and confirmed cervical cancer in HIV-seropositive women from developing countries: a systematic review.


ABSTRACT:

Background

Cervical cancer has become a major public health challenge in developing countries with a reported age-standardised incidence rate of about 17.9/100,000/year and lifetime risks approaching 1 in 20 in some settings. Evidence indicates that HIV-seropositive women are 2 to 12 times more likely to develop precancerous lesions that lead to cervical cancer than HIV-negative women. There is a lack of rigorous evidence on which treatment methods are being utilised for HIV-positive women, and this review aims to synthesise available evidence on treatment modalities for both cervical neoplasia and cervical cancer in HIV-seropositive women in developing countries.

Methods

A systematic review guided by a published protocol was conducted. Online databases including MEDLINE/Pub

SUBMITTER: Mapanga W 

PROVIDER: S-EPMC7149877 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature